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What are the causes of Dupuytren's contracture?

February 19, 2020

Dupuytren's contracture can be defined as a formation of scar tissue in or around your palm. The condition can make it nearly impossible to fully extend the fingers. 

It’s important to know the causes of Dupuytren's contracture to be able to reduce its spread. Science is yet to find the precise cause of the disease as it's still unknown. However, some factors can increase the risk of developing Dupuytren's contracture.

It’s believed that some biochemical factors can affect your palm’s tissue. Contrary to popular belief, overuse of hand is not a cause. It may lead to injuries and tendon-related problems, but it does not result in Dupuytren's contracture.

The condition is hereditary and usually runs in families. If someone in your family has the disease then there is a higher risk of you or someone else in the family falling victim. 

The risk is higher in people with a Scandivanian (Finnish, Swedish, Norwegian) or Northern European (Irish, French, Dutch, English, Scottish) background.

It has been found that the disease is more common in men compared to women. Those above 40 are at a greater risk.

Here are a few habits or factors that can put you in danger:

Poor Habits

Reports suggest that consuming alcohol can increase the risk of the diseases even though most people with Dupuytren's contracture are not alcoholics. This is whyDupuytren's contracture alcohol is one of the most commonly searched terms.

In addition to this, smoking is also linked to the disease. It may be involved in the pathogenesis of the disease by producing microvascular occlusion and subsequent fibrosis as per this study.


There are reasons to believe that diabetes increases the risk of the disease. 

While the two aren't connected, we must mention that Dupuytren's contracture is often considered a complication of diabetes. 

This report suggests that the frequency of the disease is 10x higher in diabetic individuals than in the general population.

However, the latest research on Dupuytren's contracturehighlights that only about 5 percent of the patients are diabetic but some experts believe there to be a direct connection between the two diseases.


Some reports suggest that seizures, such as those witnessed in individuals with epilepsy, can increase the risk of Dupuytren's contracture.

This report says there’s a direct connection between Dupuytren’s contracture and epilepsy and the risk increases with the duration of seizures.

There isn’t much presently known about the condition. Some experts believe that those who perform manual labor that includes vibration exposure are at a higher risk. 

You should be more careful if you’ve had prior hand trauma or one of these conditions:

  • Hyperlipidemia
  • Complex regional pain syndrome
  • Peyronie disease 

If you want to know more about the causes of Dupuytren's contracture then waste no time and get in touch with an expert today by looking at our Dupuytren's FAQ page.

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