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How is Ledderhose Disease similar to Dupuytren’s?

October 31, 2019

What is Ledderhose Disease  (plantar fibromatosis) and is it related to Dupuytren’s Contracture?

Dupuytren's Cream has been shown to help fight the symptoms and pain associated with Ledderhose Disease.

Although originally designed specifically for patients with Dupuytren’s Contracture the cream has been shown to be effective for those with Ledderhose Disease, and against the pain and inflammation associated with Trigger Finger. 

Ledderhose disease (also known as plantar fibromatosis) is very similar to Dupuytren’s contracture but affects the feet instead of the hands. Ledderhose causes the connective tissue to build up and create hard lumps on the bottoms of the feet. These lumps form along the plantar fascia, which is the band of tissue that connects your heel bone with your toes. The growths aren’t cancerous, but they can cause pain, especially when you walk.

Ledderhose disease can occur in conjunction with Dupuytren’s or on its own. Like Dupuytren’s symptoms normally begin to appear in your forties and fifties.

The primary symptom of Ledderhose disease is hard lumps on the soles of one or both of your feet. These lumps can be painful, especially when you walk and can cause pain in your foot and ankle joints.

Like Dupuytren’s the exact cause is unknown but genetics and age both play a large role. Those that also have Dupuytren’s or other connective tissue diseases are much more likely to also have Ledderhose disease. 

Similar to Dupuytren’s treatment, options are limited and not always effective. In the early stages, there is often little to no discomfort. As the lumps continue to grow soft shoe inserts may be recommended to alleviate the pressure on the lumps when walking. Cutting holes in the inserts to align with the lumps and provide additional space may provide some relief while walking. Gentle stretches, massage, and ice the sole of your foot can help with the pain. You can also try nonsteroidal anti-inflammatory drugs such as ibuprofen or naproxen to reduce pain and swelling.


Other options for treating the symptoms of Ledderhose disease include physical therapy, stretching exercises, massage of the feet, and some therapists will recommend splints that most patients find highly impractical. Steroid injections are recommended by some physicians to relieve pain and reduce inflammation. In extreme situations where the lumps are very painful, your doctor might recommend a type of surgery called fasciectomy. During this procedure, the surgeon will remove part or all of the thickened tissue from your foot. The surgery can leave scars, and Ledderhose disease can eventually come back. Cryosurgery is also another potential treatment option that works to freeze the lumps and kill the tissue however mixed reviews have been received. 

Some promising new options, such as topical creams, have also begun to be recommended for Dupuytren’s contracture and can be effective in combatting the symptoms of Ledderhose disease. Topical creams for Dupuytren's that use all-natural ingredients to help fight inflammation, swelling and have been seen to help halt stop or reverse the progression of the symptom for both Dupuytren’s contracture and Ledderhose Disease.  

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